Mulberroside A

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Mulberroside 具有肾保护、降血糖和抗糖尿病作用。

Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of melanogenesis. Mulberroside A has anti-inflammatory antiapoptotic effects. by decreasing the expressions of tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, and IL-6 and inhibiting the activation of NALP3, caspase-1, and nuclear factor-κB and the phosphorylation of extracellular signal-regulated protein kinases, the c-Jun N-terminal kinase, and p38.

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Mulberroside A (10, 20, and 40 mg/kg) decreases serum uric acid levels and increases urinary urate excretion and fractional excretion of uric acid in hyperuricemic micem. Animal Model:Male Kun-Ming mice (20±2 g) Dosage:5, 10, 20, and 40 mg/kg; the dose volume 10 mL/kg body weight Administration:Orally initiated at 9:00 a.m.Result:10, 20, and 40 mg/kg significantly increased urinary urate excretion in 24 h, resulting in a remarkable elevation of fractional excretion of uric acid (FEUA), and the highest dose completely reversed FEUA alteration of hyperuricemic mice to normal.

Mulberroside A | Mulberroside-A

Others

Other Targets

Others

Others-Field

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102841-42-9

568.52

C26H32O14

>98% (HPLC)

DMSO : ≥ 40 mg/mL; 70.36 mM

C1=CC(=C(C=C1OC2C(C(C(C(O2)CO)O)O)O)O)C=CC3=CC(=CC(=C3)OC4C(C(C(C(O4)CO)O)O)O)O

(2S,3R,4S,5S,6R)-2-[3-Hydroxy-4-[(E)-2-[3-hydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol

(-20℃)

With Ice Pack

≥ 2 years